In this paper I deal with a puzzling passage, which occurs in Metaphysics Z 13.1038b2 – 3 and where Aristotle mentions four possible meanings of substance: the substratum, the essence, the compound of these (τὸ ἐκ τούτων) and the universal. This list accords only partially with the previous one in Z 3.1028b33–36, where Aristotle mentions the substratum, the essence, the universal and the genus. Thus, Z 13’s list omits Z 3’s genus, but includes τὸ ἐκ τούτων, which is standardly used (...) by Aristotle to refer to the compound of matter and form. This is puzzling, for at least two reasons: (1) it is not clear what has happened to Z 3’s genus; (2) it is not clear what exactly is the reference of τὸ ἐκ τούτων, for the context suggests, at first glance awkwardly, that the compound in question is that of substratum and essence, and not of matter and form. These problems have led some scholars to delete τὸ ἐκ τούτων from the list. In this paper I provide two sets of arguments in order to resist the deletion. In the first set I show how, at least in principle, it would not be inaccurate to define the compound of matter and form as a “compound of substratum and essence”. In the second set, I show how, in fact, through the reference to the compound of substratum and essence, Aristotle does not want to designate, in Z 13, the hylomorphic composite. Rather, he aims to designate the notion of form regarded as universal, namely as ‘species’, which seems to reveal a peculiar sort of composition between a substratum (its genus) and an essence (its specific difference). (shrink)

ABSTRACTEmpathy represents a fundamental ability that allows for the creation and cultivation of social bonds. As part of the empathic process, individuals use their own emotional state to interpret the content and intensity of other people’s emotions. Therefore, the current study was designed to test two hypotheses: empathy for the pain of another will result in biased emotional intensity judgment; and changing one’s emotion via emotion regulation will modulate these biased judgments. To test these hypotheses, in experiment one we used (...) a modified version of a well-known task that triggers an empathic reaction We found that empathy resulted in biased emotional intensity judgment. To the best of our knowledge, this is the first demonstration of a bias in the recognition of emotional facial expressions as a function of empathy for pain. In experiment two, we replicated these findings in an independent sample, and further found that this biased emotional intensity judgment can be moderated via reappr... (shrink)

The evolutionary origin of synapses and neurons is an enigmatic subject that inspires much debate. Non-bilaterian metazoans, both with and without neurons and their closest relatives already contain many components of the molecular toolkits for synapse functions. The origin of these components and their assembly into ancient synaptic signaling machineries are particularly important in light of recent findings on the phylogeny of non-bilaterian metazoans. The evolution of synapses and neurons are often discussed only from a metazoan perspective leaving a considerable (...) gap in our understanding. By taking an integrative approach we highlight the need to consider different, but extremely relevant phyla and to include the closest unicellular relatives of metazoans, the ichthyosporeans, filastereans and choanoflagellates, to fully understand the evolutionary origin of synapses and neurons. This approach allows for a detailed understanding of when and how the first pre- and postsynaptic signaling machineries evolved. The evolutionary origin of synapses and neurons is an enigmatic subject that inspires much debate. Most of our knowledge and recent discussions are biased towards a metazoan perspective, leaving a considerable gap in our understanding. Recent work has now revealed important insights into the emergence and co-regulation of complex synaptic signaling machineries from studies in the closest unicellular relatives of metazoans. (shrink)

Consolidation of long-term memory is a highly and precisely regulated multistep process. The transcription regulator cAMP response element-binding protein (CREB) plays a key role in initiating memory consolidation. With time processing, first the cofactors are changed and, secondly, CREB gets dispensable. This ultimately changes the expressed gene program to genes required to maintain the memory. Regulation of memory consolidation also requires epigenetic mechanisms and control at the RNA level. At the neuronal circuit level, oscillation in the activity of CREB and (...) downstream factor define engram cells. Together the combination of all regulation mechanisms allows correct memory processing while keeping the process dynamic and flexible to adjust to different contexts. Also see the video abstract here https://youtu.be/BhSCSmorpEc. (shrink)

Cognitive Science, Volume 46, Issue 10, October 2022.

Although we frequently acquire knowledge and skills through social interactions, the focus of most research on learning is on individual learning. Here we characterize Interaction Based Learning, which represents the acquisition of knowledge or skill through social interactions, and compare it to Observational Learning —learning by observation. To that end, we designed a movement synchronization paradigm whereby participants learned Tai-Chi inspired movement sequences from trained teachers in two separated sessions. We used a motion capture system to track the movement of (...) 40 dyads comprised of a teacher and learner, who were randomly divided into OL or IBL groups, and calculated time-varying synchrony of three-dimensional movement velocity. While in the IBL group both the learner and the teacher could see each other through a transparent glass, in the OL group dyads interacted through a one-way mirror, such that the learners observed the teacher, but the teacher could not see the learners. Results show that although the number of movements recalled was not different between groups, we found improved movement smoothness in the IBL compared to the OL group, indicating movement acquisition was better in the IBL group. In addition, we found that motor synchronization levels in dyads improved over time, indicating that movement synchronization can be learned and retained. In the first session, the IBL group, but not the OL group, showed a significant improvement in synchronization. This suggests that dyadic interaction is important for learning movement sequences, and that bidirectional communication of signals and mutual feedback are essential for the consolidation of motor learning. (shrink)

The authors focus on four major thematic areas – the reform of church, the reform of theology, the reform of perspective, and the reform of method – which together encompasses the breadth and depth of Cusanus’ own reform initiatives.

Despite the challenges associated with virtually mediated communication, remote collaboration is a defining characteristic of online multiplayer gaming communities. Inspired by the teamwork exhibited by players in first-person shooter games, this study investigated the verbal and behavioral coordination of four-player teams playing a cooperative online video game. The game, Desert Herding, involved teams consisting of three ground players and one drone operator tasked to locate, corral, and contain evasive robot agents scattered across a large desert environment. Ground players could move (...) throughout the environment, while the drone operator’s role was akin to that of a “spectator” with a bird’s-eye view, with access to veridical information of the locations of teammates and the to-be-corralled agents. Categorical recurrence quantification analysis was used to measure the communication dynamics of teams as they completed the task. Demands on coordination were manipulated by varying the ground players’ ability to observe the environment with the use of game “fog.” Results show that catRQA was sensitive to changes to task visibility, with reductions in task visibility reorganizing how participants conversed during the game to maintain team situation awareness. The results are discussed in the context of future work that can address how team coordination can be augmented with the inclusion of artificial agents, as synthetic teammates. (shrink)

The purpose of socially responsible investing (SRI) is to: (1) allow investors to reflect their personal values and ethics in their choices, and (2) encourage companies to improve their ethical, social, and environmental performance. In order to achieve these ends, the means SRI fund managers employ include the use of negative screening, or the exclusion of companies involved in "sinful" industries. We argue that there are problems with this methodology, both at a theoretical and at a practical level. As a (...) consequence, current SRI offerings cannot accurately reflect the values and ethical beliefs they propose to represent. Moreover, the use of a priori criteria is potentially misleading, as we show by discussing examples of glue and wine making. Applying this flawed approach SRI funds fail to influence the direction of the firms they deem most in need of redirecting. Rather than engaging in the simple a priori assumption that some industries are "saints" while others are "sinners" (Freeman, 2007) we suggest a new framework upon which the SRI screening methodology could be grounded. Embracing the philosophical tradition of American pragmatism, we suggest that SRI methodology could be improved by engaging in an analysis based on (1) the actual impacts of the company's products and services, (2) the company's relationships with its specific, real stakeholders, and (3) the contingent environment (social, economic, political, legal, and cultural) in which the business operates. (shrink)

James Bryson’s The Christian Platonism of Thomas Jackson offers the first comprehensive study of the Oxford Platonist Thomas Jackson. While Jackson is by no means unknown to early modern historians...

Ce bref article propose un panorama des différentes approches théoriques et méthodologiques pour analyser le néolibéralisme. Il s’attache tout spécialement à définir les approches politico-économiques et gouvernementales (et dans quelle mesure elles s’opposent ou se combinent) et plaide en faveur d’une critique du néolibéralisme mieux construite sur le plan théorique et méthodologique dans le champ des Media Studies. En soulignant l’hétérogénéité des modes d’analyse d’un objet tel que le néolibéralisme, ainsi que les différences dans la manière dont ces approches se (...) déploient dans d’autres domaines des Studies, il préconisera donc d’appliquer ces regards critiques à la recherche menée également au sein de multiples disciplines dans d’autres pays (comme la France). (shrink)

Ce bref article propose un panorama des différentes approches théoriques et méthodologiques pour analyser le néolibéralisme. Il s’attache tout spécialement à définir les approches politico-économiques et gouvernementales (et dans quelle mesure elles s’opposent ou se combinent) et plaide en faveur d’une critique du néolibéralisme mieux construite sur le plan théorique et méthodologique dans le champ des Media Studies. En soulignant l’hétérogénéité des modes d’analyse d’un objet tel que le néolibéralisme, ainsi que les différences dans la manière dont ces approches se (...) déploient dans d’autres domaines des Studies, il préconisera donc d’appliquer ces regards critiques à la recherche menée également au sein de multiples disciplines dans d’autres pays (comme la France). (shrink)

The Prologue offers an overview of the Reformation of method from Augustine of Hippo through to the Ramist movement, providing an orientation to the rest of the book. It highlights and explains an important nexus of Realism, exemplarism and illumination fundamental to Ramism. Beginning with Augustine it shows how these themes coalesced into a distinctive Christian philosophy taken up and refined by Franciscans such as Bonaventure of Bagnoregio and John Duns Scotus, as well as by Ramon Lull, the Franciscan-inspired encyclopaedist. (...) It traces the continuation of this methodological impulse into the Platonism and Christian humanism of the Renaissance, highlighting especially the topical and Realist (Scotistic) reform of logic pioneered by Lorenzo Valla and Rudolph Agricola. It concludes by showing the reception of this topical and biblical reform in Philipp Melanchthon and the movement of Reformed scholasticism, revealing Reformed Scotism and Christian philosophy as important preconditions for Ramism. (shrink)

In recent years evidence has emerged of the considerable influence of Scotist metaphysics on the Reformed scholasticism of the seventeenth century. One of the figures often named in connection with this Scotist revival is Samuel Rutherford (1600–61), who was one of the most important Scottish theologians of the seventeenth century. Focussing on Rutherford’s maximalist doctrine of providence, this article demonstrates his profound debt to key Scotist philosophical devices. In structuring these concepts, however, it is demonstrated that Rutherford is influenced not (...) so much by Scotus directly but rather much more by the modified Scotism of Thomas Bradwardine, the fourteenth-century Augustinian theologian. In particular, Bradwardine is revealed as the key influence on Rutherford’s modal theory and his sophisticated account of divine concourse. The paper concludes by arguing that Bradwardine’s influence on Rutherford suggests the need to take a broader view of the late medieval influence on Reformed scholasticism than is currently the case. (shrink)

The objectives of this study were to develop a high-density chromosome bin map of homoeologous group 7 in hexaploid wheat, to identify gene distribution in these chromosomes, and to perform comparative studies of wheat with rice and barley. We mapped 2148 loci from 919 EST clones onto group 7 chromosomes of wheat. In the majority of cases the numbers of loci were significantly lower in the centromeric regions and tended to increase in the distal regions. The level of duplicated loci (...) in this group was 24% with most of these loci being localized toward the distal regions. One hundred nineteen EST probes that hybridized to three fragments and mapped to the three group 7 chromosomes were designated landmark probes and were used to construct a consensus homoeologous group 7 map. An additional 49 probes that mapped to 7AS, 7DS, and the ancestral translocated segment involving 7BS also were designated landmarks. Landmark probe orders and comparative maps of wheat, rice, and barley were produced on the basis of corresponding rice BAC/PAC and genetic markers that mapped on chromosomes 6 and 8 of rice. Identification of landmark ESTs and development of consensus maps may provide a framework of conserved coding regions predating the evolution of wheat genomes. (shrink)

Background: Mental healthcare needs person-tailored interventions. Experience Sampling Method (ESM) can provide daily life monitoring of personal experiences. This study aims to operationalize and test a measure of momentary reward-related Quality of Life (rQoL). Intuitively, quality of life improves by spending more time on rewarding experiences. ESM clinical interventions can use this information to coach patients to find a realistic, optimal balance of positive experiences (maximize reward) in daily life. rQoL combines the frequency of engaging in a relevant context (a (...) ‘behavior setting’) with concurrent (positive) affect. High rQoL occurs when the most frequent behavior settings are combined with positive affect or infrequent behavior settings co-occur with low positive affect. Methods: Resampling procedures (Monte Carlo experiments) were applied to assess the reliability of rQoL using various behavior setting definitions under different sampling circumstances, for real or virtual subjects with low-, average- and high contextual variability. Furthermore, resampling was used to assess whether rQoL is a distinct concept from positive affect. Virtual ESM beep datasets were extracted from 1058 valid ESM observations for virtual and real subjects. Results: Behavior settings defined by Who-What contextual information were most informative. Simulations of at least 100 ESM observations are needed for reliable assessment. Virtual ESM beep datasets of a real subject can be defined by Who-What-Where behavior setting combinations. Large sample sizes are necessary for reliable rQoL assessments, except for subjects with low contextual variability. rQoL is distinct from positive affect. Conclusion: rQoL is a feasible concept. Monte Carlo experiments should be used to assess the reliable implementation of an ESM statistic. Future research in ESM should asses the behavior of summary statistics under different sampling situations. This exploration is especially relevant in clinical implementation, where often only small datasets are available. (shrink)

In this paper, we put forward an interdisciplinary framework describing different levels of self-representations, namely non-conceptual, conceptual and propositional self-representations. We argue that these different levels of self-representation are differently affected by cultural upbringing: while propositional self-representations rely on “theoretical” concepts and are thus strongly influenced by cultural upbringing, non-conceptual self-representations are uniform across cultures and thus universal. This differentiation offers a theoretical specification of the distinction between an independent and interdependent self-construal put forward in cross-cultural psychology. Hence, this does (...) not only allow for a deeper understanding of different self-conceptions, but also for a formulation of new hypotheses regarding the cultural influence on self-representations. As one example, we will highlight the role of the proposed levels of self-representation for emotional experience and formulate some major implications of our interdisciplinary framework for future empirical research. (shrink)

What constitutes a just war? How does race matter in America? Are the interests of corporations the same as those of the public when it comes to the environment or public health? Middle and high school history, literature, and science classes abound with important moral, social, and political questions. But under pressure to cover required materials and out of fear of raising controversy, teachers often avoid classroom discussions of questions of profound importance to students and to society. This book investigates (...) how schools can responsibly take an active role in moral education while honoring their academic mission. Using extensive observations in public, Catholic, and Jewish high schools, Katherine Simon analyzes the ways in which teachers avoid or address moral questions raised by students and implicit in course materials. She examines how morally charged issues may be taught responsibly in a diverse democracy. And in an afterword that teachers and teacher educators will find particularly useful, Simon provides practical tools and strategies for structuring discussion and designing units to help teachers explore moral issues more deeply with their middle and high school students. (shrink)

What constitutes a just war? How does race matter in America? Are the interests of corporations the same as those of the public when it comes to the environment or public health? Middle and high school history, literature, and science classes abound with important moral, social, and political questions. But under pressure to cover required materials and out of fear of raising controversy, teachers often avoid classroom discussions of questions of profound importance to students and to society. This book investigates (...) how schools can responsibly take an active role in moral education while honoring their academic mission. Using extensive observations in public, Catholic, and Jewish high schools, Katherine Simon analyzes the ways in which teachers avoid or address moral questions raised by students and implicit in course materials. She examines how morally charged issues may be taught responsibly in a diverse democracy. And in an afterword that teachers and teacher educators will find particularly useful, Simon provides practical tools and strategies for structuring discussion and designing units to help teachers explore moral issues more deeply with their middle and high school students. (shrink)

At the forefront of international concerns about global legislation and regulation, a host of noted environmentalists and business ethicists examine ethical issues in consumption from the points of view of environmental sustainability, economic development, and free enterprise.

This dissertation examines the phenomenology of self-awareness in an attempt to get clear on the nature of our 'basic sense of self'. I argue that our self-understanding is typically muddled by a prevalent but false metaphysical view that I refer to as 'the quasi-Cartesian view'. I begin with a diagnosis of this quasi-Cartesian view of the self and self-awareness, and argue that there are two main reasons for one might hold this view: on the one hand, we may have our (...) phenomenology colored by false metaphysical preconceptions; on the other, we may end up holding this view as a result of commitments held in the philosophy of mind. I try to cure us of this view by showing that it is neither defensible when presented with counter-arguments, nor fits the phenomenological data of our own experience. I next develop a positive account of what our basic sense of self is like when we have shed the distorting quasi-Cartesian preconceptions. I argue that in basic experience, we experience ourselves as bodily agents; moreover, I develop a transcendental argument to the effect that we must be embodied agents in order for us to have the kinds of experience that we do have. I next turn to an examination of the Heideggerian claim that we are self-interpreting animals in part constituted by our own self-interpretations in an attempt to determine the truth as well as the scope of this claim. My conclusion is that we can truthfully be said to be partly constituted by our own self-interpretations, but that we have but a limited authority as to the 'rightness' of an interpretation. Thus there are strict limits to our ability to be self-constituting. (shrink)